Search results for "infection rate"

showing 4 items of 4 documents

2016

AbstractUnderstanding the dynamics of zoonotic pathogens in their reservoir host populations is a prerequisite for predicting and preventing human disease epidemics. The human infection risk of Puumala hantavirus (PUUV) is highest in northern Europe, where populations of the rodent host (bank vole, Myodes glareolus) undergo cyclic fluctuations. We conducted a 7-year capture-mark-recapture study to monitor seasonal and multiannual patterns of the PUUV infection rate in bank vole populations exhibiting a 3-year density cycle. Infected bank voles were most abundant in mid-winter months during years of increasing or peak host density. Prevalence of PUUV infection in bank voles exhibited a regul…

MYODES-GLAREOLUS0301 basic medicineRodentSIN-NOMBRE-VIRUSPuumala hantavirus030231 tropical medicineSEED PRODUCTIONzoonotic pathogensinfection rateRODENT POPULATIONSHOST POPULATIONS03 medical and health sciences0302 clinical medicinebiology.animalMyodes glareolusNephropathia epidemicamedicineSOUTHWESTERN UNITED-STATESbank voleCLETHRIONOMYS-GLAREOLUSHantavirusMATERNAL ANTIBODIESMultidisciplinarybiologyEcologySin Nombre virusTransmission (medicine)ta1183biology.organism_classificationmedicine.diseasecyclic fluctuationsNEPHROPATHIA-EPIDEMICA3. Good healthBank vole030104 developmental biologyDEER MICEArvicolinaeta1181Puumala virus3111 BiomedicineScientific Reports
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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

2021

Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…

MaleCOVID-19 Vaccinesafe surgery; vaccination modelling; COVID-19Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]MULTICENTERComorbidity030230 surgery0302 clinical medicinephase 3 clinical trial (topic)Case fatality rateProspective StudiesSARS-CoV-2 Vaccination Safe surgeryCOVID-19/epidemiologySARS-CoV-2 ; vaccination ; safe surgeryeducation.field_of_studycase fatality rateVaccinationVaccinationAdolescent; Adult; Aged; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Preoperative Period; Prospective Studies; SARS-CoV-2; Vaccination; Young Adulthealth care policyElective Surgical Procedures030220 oncology & carcinogenesisvaccination modellingPreoperative PeriodCOVID-19; SARS-CoV-2; cancer; vaccination; outcome; mortality; infection; modellingCohort studyprospective studyHumanmedicine.medical_specialtyArticle03 medical and health sciencesSARS-CoV-2 vaccinationSDG 3 - Good Health and Well-beingCOVID-19 Vaccines/pharmacologyHumansVaccination/methodsElective surgeryeducationAgedScience & TechnologyElective Surgical Procedureadult; aged; Article; cancer grading; cancer surgery; case fatality rate; computer assisted tomography; elective surgery; female; follow up; health care policy; human; incidence; infection rate; infection risk; major clinical study; male; middle aged; mortality; outcome assessment; phase 3 clinical trial (topic); preoperative care; prospective study; sensitivity analysis; seroprevalence; Severe acute respiratory syndrome coronavirus 2; vaccination; young adult; COVID-19; COVID-19 Vaccines; Comorbidity; Elective Surgical Procedures; Postoperative Complications; Preoperative Period; SARS-CoV-2; Vaccination; surgery.Cura preoperatòriamajor clinical studymortalityinfectionProspective StudieincidenceSurgeryHuman medicinePostoperative Complication610 Medizin und GesundheitAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALEcomputer assisted tomographyESTUDOS PROSPECTIVOSsurgerysafe surgeryPostoperative Complicationssensitivity analysisSevere acute respiratory syndrome coronavirus 2preoperative careVacunacióProspective cohort studyseroprevalenceIncidence (epidemiology)covidElective Surgical Procedures/methodsMiddle Agedcancer gradingCOVID vaccinationoutcome/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSARS-CoV-2; vaccination; surgeryOriginal ArticleFemalecancer surgeryAcademicSubjects/MED00010Life Sciences & BiomedicineAdultCOVID-19 VaccinesAdolescentinternational prospective cohort studyPostoperative Complications/prevention & controlPopulationinfection rateSARS-CoV-2/immunologyNOmodellingYoung Adultmedicinefollow upcancerddc:610infection riskoutcome assessmentLS7_4business.industrySARS-CoV-2Number needed to vaccinatePreoperative careCOVID-193126 Surgery anesthesiology intensive care radiologySettore MED/18Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]elective surgeryEmergency medicinebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyThe British Journal of Surgery
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Building a benchmark through active surveillance of intensive care unit-acquired infections: the Italian network SPIN-UTI.

2010

The Italian Nosocomial Infections Surveillance in Intensive Care Units (ICUs) (SPIN-UTI) project of the Italian Study Group of Hospital Hygiene (GISIO - SItI) was undertaken to ensure standardisation of definitions, data collection and reporting procedures using the Hospital in Europe Link for Infection Control through Surveillance (HELICS)-ICU benchmark. Before starting surveillance, participant ICUs met in order to involve the key stakeholders in the project through participation in planning. Four electronic data forms for web-based data collection were designed. The six-month patient-based prospective survey was undertaken from November 2006 to May 2007, preceded by a one-month surveilla…

Microbiology (medical)Malemedicine.medical_specialtylaw.inventioninfection rates; device utilisation ratio; active surveillancelawIntensive careEpidemiologymedicineInfection controlHumansCumulative incidenceIntensive care medicineCross InfectionInfection ControlRisk Managementbusiness.industryIncidence (epidemiology)Data CollectionBacterial pneumoniaGeneral MedicineMiddle Agedmedicine.diseaseIntensive care unitIntensive Care UnitsInfectious DiseasesItalyEmergency medicineElectronic dataFemalebusinessSentinel SurveillanceThe Journal of hospital infection
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Administration of Triclabendazole Is Safe and Effective in Controlling Fascioliasis in an Endemic Community of the Bolivian Altiplano

2012

Background Emergence of human fascioliasis prompted a worldwide control initiative including a pilot study in a few countries. Two hyperendemic areas were chosen: Huacullani, Northern Altiplano, Bolivia, representing the Altiplanic transmission pattern with high prevalences and intensities; Cajamarca valley, Peru, representing the valley pattern with high prevalences but low intensities. Coprological sample collection, transport and study procedures were analyzed to improve individual diagnosis and subsequent treatments and surveillance activities. Therefore, a coproantigen-detection technique (MM3-COPRO ELISA) was evaluated, using classical techniques for egg detection for comparison. Meth…

MaleVeterinary medicineRC955-962law.inventionFecesfluids and secretionslawArctic medicine. Tropical medicinePeruMass ScreeningChildEggs per gramInfectious DiseasesTransmission (mechanics)Human fascioliasisChild PreschoolMedicineFemaledisease severityPublic HealthSample collectiondisease surveillanceoptical densityPublic aspects of medicineRA1-1270//purl.org/pe-repo/ocde/ford#3.03.06 [https]Research ArticleTest EvaluationNeglected Tropical DiseasesFascioliasisBoliviaFasciolosisAdolescentprevalenceinfection rateEnzyme-Linked Immunosorbent AssayBiologySensitivity and SpecificitySpecimen HandlingDiagnostic Medicineparasitic diseasesParasitic DiseasesHumansfeces analysisdiagnostic test accuracy studyparasite identificationcoproantigen detection test|endemic diseaseMass screeningFecesClinical Laboratory TechniquesPublic Health Environmental and Occupational HealthGold standard (test)Fasciola hepaticaantigen detectionenzyme linked immunosorbent assayParasitologyAntigens HelminthParasitology
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